Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men

Dietary carbohydrates and insulin have been suggested to play causal roles in the pathological accumulation of body fat ( 1- 4). According to this carbohydrate-insulin model of obesity, an increased proportion of the diet as carbohydrates results in elevated insulin secretion that suppresses the release of fatty acids into circulation and directs circulating fat toward storage.